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Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway
Long non-coding RNAs (lncRNAs) are key regulatory molecules, but unlike with other RNAs, the direct link between their tertiary structure motifs and their function has proven elusive. Here we report structural and functional studies of human maternally expressed gene 3 (MEG3), a tumor suppressor lnc...
Autores principales: | Uroda, Tina, Anastasakou, Eleni, Rossi, Annalisa, Teulon, Jean-Marie, Pellequer, Jean-Luc, Annibale, Paolo, Pessey, Ombeline, Inga, Alberto, Chillón, Isabel, Marcia, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739425/ https://www.ncbi.nlm.nih.gov/pubmed/31444106 http://dx.doi.org/10.1016/j.molcel.2019.07.025 |
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