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Substitution of cysteines in the yeast viral killer toxin K1 precursor reveals novel insights in heterodimer formation and immunity
The killer toxin K1 is a virally encoded fungal A/B toxin acting by disrupting plasma membrane integrity. The connection of α and β constitutes a critical feature for toxin biology and for decades the formation of three disulphide bonds linking the major toxin subunits was accepted as status quo. Du...
Autores principales: | Gier, Stefanie, Lermen, Matthias, Schmitt, Manfred J., Breinig, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739482/ https://www.ncbi.nlm.nih.gov/pubmed/31511600 http://dx.doi.org/10.1038/s41598-019-49621-z |
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