Cargando…
Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation
As humans age, normal tissues, such as the esophageal epithelium, become a patchwork of mutant clones. Some mutations are under positive selection, conferring a competitive advantage over wild-type cells. We speculated that altering the selective pressure on mutant cell populations may cause them to...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739485/ https://www.ncbi.nlm.nih.gov/pubmed/31327664 http://dx.doi.org/10.1016/j.stem.2019.06.011 |