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Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

BACKGROUND: Intrahepatic cholestasis of pregnancy, characterised by maternal pruritus and increased serum bile acid concentrations, is associated with increased rates of stillbirth, preterm birth, and neonatal unit admission. Ursodeoxycholic acid is widely used as a treatment without an adequate evi...

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Detalles Bibliográficos
Autores principales: Chappell, Lucy C, Bell, Jennifer L, Smith, Anne, Linsell, Louise, Juszczak, Edmund, Dixon, Peter H, Chambers, Jenny, Hunter, Rachael, Dorling, Jon, Williamson, Catherine, Thornton, Jim G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739598/
https://www.ncbi.nlm.nih.gov/pubmed/31378395
http://dx.doi.org/10.1016/S0140-6736(19)31270-X