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Ligand Binding Site Structure Shapes Folding, Assembly and Degradation of Homomeric Protein Complexes
Ligand binding site structure has profound consequences for the evolution of function of protein complexes, particularly in homomers—complexes comprising multiple copies of the same protein. Previously, we have shown that homomers with multichain binding sites (MBSs) are characterized by more conser...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739599/ https://www.ncbi.nlm.nih.gov/pubmed/31306664 http://dx.doi.org/10.1016/j.jmb.2019.07.014 |