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A Genetic Approach to the Association Between PCSK9 and Sepsis

IMPORTANCE: Whether the PCSK9 gene is associated with the progress from infection to sepsis is unknown to date. OBJECTIVE: To test the associations between PCSK9 genetic variants, a PCSK9 genetic risk score (GRS), or genetically estimated PCSK9 expression levels and the risk of sepsis among patients...

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Detalles Bibliográficos
Autores principales: Feng, QiPing, Wei, Wei-Qi, Chaugai, Sandip, Carranza Leon, Barbara G., Kawai, Vivian, Carranza Leon, Daniel A., Jiang, Lan, Zhong, Xue, Liu, Ge, Ihegword, Andrea, Shaffer, Christian M., Linton, MacRae F., Chung, Cecilia P., Stein, C. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739725/
https://www.ncbi.nlm.nih.gov/pubmed/31509211
http://dx.doi.org/10.1001/jamanetworkopen.2019.11130