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Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome

OBJECTIVE: The objective of this study is to explore the relationships of the effects of CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high platelet responsiveness (HPR) by thrombelastography in patients with acute coronary syndrome (ACS). METHODS: 459 ACS patien...

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Detalles Bibliográficos
Autores principales: Peng, Wenxing, Shi, Xiujin, Xu, Xiaoyu, Lin, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739775/
https://www.ncbi.nlm.nih.gov/pubmed/31772608
http://dx.doi.org/10.1155/2019/3470145