Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation

Knowledge of the host factors required for norovirus replication has been hindered by the challenges associated with culturing human noroviruses. We have combined proteomic analysis of the viral translation and replication complexes with a CRISPR screen, to identify host factors required for norovir...

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Detalles Bibliográficos
Autores principales: Hosmillo, Myra, Lu, Jia, McAllaster, Michael R, Eaglesham, James B, Wang, Xinjie, Emmott, Edward, Domingues, Patricia, Chaudhry, Yasmin, Fitzmaurice, Tim J, Tung, Matthew KH, Panas, Marc Dominik, McInerney, Gerald, Locker, Nicolas, Wilen, Craig B, Goodfellow, Ian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739877/
https://www.ncbi.nlm.nih.gov/pubmed/31403400
http://dx.doi.org/10.7554/eLife.46681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739877/
https://www.ncbi.nlm.nih.gov/pubmed/31403400
http://dx.doi.org/10.7554/eLife.46681

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