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Deciphering epigenomic code for cell differentiation using deep learning

BACKGROUND: Although DNA sequence plays a crucial role in establishing the unique epigenome of a cell type, little is known about the sequence determinants that lead to the unique epigenomes of different cell types produced during cell differentiation. To fill this gap, we employed two types of deep...

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Detalles Bibliográficos
Autores principales: Ni, Pengyu, Su, Zhengchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739944/
https://www.ncbi.nlm.nih.gov/pubmed/31510916
http://dx.doi.org/10.1186/s12864-019-6072-8