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Clinical outcomes stratified by baseline functional class after initial combination therapy for pulmonary arterial hypertension

BACKGROUND: Initial combination therapy with ambrisentan and tadalafil reduced the risk of clinical failure events for treatment-naïve participants with pulmonary arterial hypertension (PAH) as compared to monotherapy. Previous studies in PAH have demonstrated greater treatment benefits in more symp...

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Detalles Bibliográficos
Autores principales: White, R. James, Vonk-Noordegraaf, Anton, Rosenkranz, Stephan, Oudiz, Ronald J., McLaughlin, Vallerie V., Hoeper, Marius M., Grünig, Ekkehard, Ghofrani, Hossein-Ardeschir, Chakinala, Murali M., Barberà, Joan A., Blair, Christiana, Langley, Jonathan, Frost, Adaani E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739949/
https://www.ncbi.nlm.nih.gov/pubmed/31511080
http://dx.doi.org/10.1186/s12931-019-1180-1