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Discordant amyloid-β PET and CSF biomarkers and its clinical consequences

BACKGROUND: In vivo, high cerebral amyloid-β load has been associated with (i) reduced concentrations of Aβ(42) in cerebrospinal fluid and (ii) increased retention using amyloid-β positron emission tomography. Although these two amyloid-β biomarkers generally show good correspondence, ~ 10–20% of ca...

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Detalles Bibliográficos
Autores principales: de Wilde, Arno, Reimand, Juhan, Teunissen, Charlotte E., Zwan, Marissa, Windhorst, Albert D., Boellaard, Ronald, van der Flier, Wiesje M., Scheltens, Philip, van Berckel, Bart N. M., Bouwman, Femke, Ossenkoppele, Rik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739952/
https://www.ncbi.nlm.nih.gov/pubmed/31511058
http://dx.doi.org/10.1186/s13195-019-0532-x