Cargando…
Evolving Concept of Activity Cliffs
[Image: see text] Activity cliffs (ACs) are generally defined as pairs or groups of structurally similar compounds that are active against the same target but have large differences in potency. Accordingly, ACs capture chemical modifications that strongly influence biological activity. Therefore, th...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2019
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740043/ https://www.ncbi.nlm.nih.gov/pubmed/31528788 http://dx.doi.org/10.1021/acsomega.9b02221 |