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Conserved NDR/LATS kinase controls RAS GTPase activity to regulate cell growth and chronological lifespan

Adaptation to the nutritional environment is critical for all cells. RAS GTPase is a highly conserved GTP-binding protein with crucial functions for cell growth and differentiation in response to environmental conditions. Here, we describe a novel mechanism connecting RAS GTPase to nutrient availabi...

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Detalles Bibliográficos
Autores principales: Chen, Chuan, Rodriguez Pino, Marbelys, Haller, Patrick Roman, Verde, Fulvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6740195/
https://www.ncbi.nlm.nih.gov/pubmed/31390298
http://dx.doi.org/10.1091/mbc.E19-03-0172