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Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

Planar cell polarity (PCP) regulates coordinated cellular polarity among neighboring cells to establish a polarity axis parallel to the plane of the tissue. Disruption in PCP results in a range of developmental anomalies and diseases. A key feature of PCP is the polarized and asymmetric localization...

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Detalles Bibliográficos
Autores principales: Tower-Gilchrist, Cristy, Zlatic, Stephanie A., Yu, Dehong, Chang, Qing, Wu, Hao, Lin, Xi, Faundez, Victor, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741063/
https://www.ncbi.nlm.nih.gov/pubmed/31268833
http://dx.doi.org/10.1091/mbc.E16-08-0592