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Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear
Planar cell polarity (PCP) regulates coordinated cellular polarity among neighboring cells to establish a polarity axis parallel to the plane of the tissue. Disruption in PCP results in a range of developmental anomalies and diseases. A key feature of PCP is the polarized and asymmetric localization...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741063/ https://www.ncbi.nlm.nih.gov/pubmed/31268833 http://dx.doi.org/10.1091/mbc.E16-08-0592 |