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PI3Kβ links integrin activation and PI(3,4)P(2) production during invadopodial maturation
The invasion of tumor cells from the primary tumor is mediated by invadopodia, actin-rich protrusive organelles that secrete matrix metalloproteases and degrade the extracellular matrix. This coupling between protrusive activity and matrix degradation facilitates tumor invasion. We previously report...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741064/ https://www.ncbi.nlm.nih.gov/pubmed/31318314 http://dx.doi.org/10.1091/mbc.E19-03-0182 |