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PI3Kβ links integrin activation and PI(3,4)P(2) production during invadopodial maturation

The invasion of tumor cells from the primary tumor is mediated by invadopodia, actin-rich protrusive organelles that secrete matrix metalloproteases and degrade the extracellular matrix. This coupling between protrusive activity and matrix degradation facilitates tumor invasion. We previously report...

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Detalles Bibliográficos
Autores principales:	Erami, Zahra, Heitz, Samantha, Bresnick, Anne R., Backer, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741064/ https://www.ncbi.nlm.nih.gov/pubmed/31318314 http://dx.doi.org/10.1091/mbc.E19-03-0182

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