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Key within-membrane residues and precursor dosage impact the allotopic expression of yeast subunit II of cytochrome c oxidase
Experimentally relocating mitochondrial genes to the nucleus for functional expression (allotopic expression) is a challenging process. The high hydrophobicity of mitochondria-encoded proteins seems to be one of the main factors preventing this allotopic expression. We focused on subunit II of cytoc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741066/ https://www.ncbi.nlm.nih.gov/pubmed/31318312 http://dx.doi.org/10.1091/mbc.E18-12-0788 |