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Deficiency of D‐alanyl‐D‐alanine ligase A attenuated cell division and greatly altered the proteome of Mycobacterium smegmatis
D‐Alanyl‐D‐alanine ligase A (DdlA) catalyses the dimerization of two D‐alanines yielding D‐alanyl‐D‐alanine required for mycobacterial peptidoglycan biosynthesis, and is a promising antimycobacterial drug target. To better understand the roles of DdlA in mycobacteria in vivo, we established a cell m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741128/ https://www.ncbi.nlm.nih.gov/pubmed/30828981 http://dx.doi.org/10.1002/mbo3.819 |