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Deficiency of D‐alanyl‐D‐alanine ligase A attenuated cell division and greatly altered the proteome of Mycobacterium smegmatis

D‐Alanyl‐D‐alanine ligase A (DdlA) catalyses the dimerization of two D‐alanines yielding D‐alanyl‐D‐alanine required for mycobacterial peptidoglycan biosynthesis, and is a promising antimycobacterial drug target. To better understand the roles of DdlA in mycobacteria in vivo, we established a cell m...

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Detalles Bibliográficos
Autores principales: Chen, Yingfei, Xu, Yuefei, Yang, Shufeng, Li, Sheng, Ding, Wenyong, Zhang, Wenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741128/
https://www.ncbi.nlm.nih.gov/pubmed/30828981
http://dx.doi.org/10.1002/mbo3.819