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Hypoxia-induced internalization of connexin 26 and connexin 43 in pulmonary epithelial cells is involved in the occurrence of non-small cell lung cancer via the P53/MDM2 signaling pathway

Reports have highlighted an association between connexins (CXs) or gap junction proteins and non-small cell lung cancer (NSCLC). In the present study, it was aimed to elucidate the regulatory mechanism of CX26 and CX43 under hypoxic conditions in NSCLC. Clinical samples were collected for analysis o...

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Detalles Bibliográficos
Autores principales: Zeng, Shang-Gan, Lin, Xiang, Liu, Ji-Chun, Zhou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741836/
https://www.ncbi.nlm.nih.gov/pubmed/31485592
http://dx.doi.org/10.3892/ijo.2019.4867