Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway

Bromodomain and extraterminal domain proteins, especially bromodomain-containing protein 4 (Brd4), have recently emerged as therapeutic targets for several cancers, although the role and mechanism of Brd4 in glioblastoma multiforme (GBM) are unclear. In this study, we aimed to explore the underlying...

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Detalles Bibliográficos
Autores principales: Wen, Naiyan, Guo, Baofeng, Zheng, Hongwu, Xu, Libo, Liang, Hang, Wang, Qian, Wang, Ding, Chen, Xuyang, Zhang, Shengnan, Li, Yang, Zhang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741838/
https://www.ncbi.nlm.nih.gov/pubmed/31485609
http://dx.doi.org/10.3892/ijo.2019.4863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741838/
https://www.ncbi.nlm.nih.gov/pubmed/31485609
http://dx.doi.org/10.3892/ijo.2019.4863

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