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Construction and characterization of a truncated tissue factor-coagulation-based composite system for selective thrombosis in tumor blood vessels
The selective induction of tumor vascular thrombosis using truncated tissue factor (tTF) delivered via a target ligand is a promising novel antitumor strategy. In the present study, an anti-neuropilin-1 (NRP-1) monoclonal antibody (mAb)-streptavidin (SA):tTF-biotin (B) composite system was establish...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741845/ https://www.ncbi.nlm.nih.gov/pubmed/31432158 http://dx.doi.org/10.3892/ijo.2019.4855 |