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Computational tools to detect signatures of mutational processes in DNA from tumours: A review and empirical comparison of performance
Mutational signatures refer to patterns in the occurrence of somatic mutations that might be uniquely ascribed to particular mutational process. Tumour mutation catalogues can reveal mutational signatures but are often consistent with the mutation spectra produced by a variety of mutagens. To date,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741849/ https://www.ncbi.nlm.nih.gov/pubmed/31513583 http://dx.doi.org/10.1371/journal.pone.0221235 |