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Generation of a protective murine monoclonal antibody against the stem of influenza hemagglutinins from group 1 viruses and identification of resistance mutations against it

Vaccines that elicit broadly cross-neutralizing antibodies, including antibodies that target the conserved stem of hemagglutinin (HA), are being developed as a strategy for next-generation influenza vaccines that protect against influenza across multiple years. However, efficient induction of cross-...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Vassell, Russell, Song, Hyo Sook, Chen, Qiong, Keller, Paul W., Verma, Swati, Alvarado-Facundo, Esmeralda, Wan, Hongquan, Schmeisser, Falko, Meseda, Clement A., Weir, Jerry P., Weiss, Carol D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742228/
https://www.ncbi.nlm.nih.gov/pubmed/31513662
http://dx.doi.org/10.1371/journal.pone.0222436