Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption

Damaged acinar cells play a passive role in activating pancreatic stellate cells (PSCs) via recruitment of immune cells that subsequently activate PSCs. However, whether acinar cells directly contribute to PSC activation is unknown. Here, we report that the Hippo pathway, a well-known regulator of p...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Gao, Ming, Nipper, Michael, Deng, Janice, Sharkey, Francis E., Johnson, Randy L., Crawford, Howard C., Chen, Yidong, Wang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742234/
https://www.ncbi.nlm.nih.gov/pubmed/31513574
http://dx.doi.org/10.1371/journal.pbio.3000418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742234/
https://www.ncbi.nlm.nih.gov/pubmed/31513574
http://dx.doi.org/10.1371/journal.pbio.3000418

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