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Development of highly efficient protocols for extraction and amplification of cytomegalovirus DNA from dried blood spots for detection and genotyping of polymorphic immunomodulatory genes

Congenital cytomegalovirus (CMV) infection is a major cause of birth defects ranging from developmental disorders to stillbirth. Most newborns affected by CMV do not present with symptoms at birth but are at risk of sequelae at later stages of their childhood. Stored dried blood spots (DBS) taken at...

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Detalles Bibliográficos
Autores principales: Berg, Christian, Friis, Martin B., Rosenkilde, Mette M., Benfield, Thomas, Nielsen, Lene, Lüttichau, Hans R., Sundelin, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742235/
https://www.ncbi.nlm.nih.gov/pubmed/31513621
http://dx.doi.org/10.1371/journal.pone.0222053