PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma

Polycomb repressive complex 2 (PRC2) is a chromatin binding complex that represses gene expression by methylating histone H3 at K27 to establish repressed chromatin domains. PRC2 can either regulate genes directly through the methyltransferase activity of its component EZH2 or indirectly by regulati...

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Detalles Bibliográficos
Autores principales: Shivram, Haridha, Le, Steven V., Iyer, Vishwanath R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742368/
https://www.ncbi.nlm.nih.gov/pubmed/31513636
http://dx.doi.org/10.1371/journal.pone.0222435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742368/
https://www.ncbi.nlm.nih.gov/pubmed/31513636
http://dx.doi.org/10.1371/journal.pone.0222435

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