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PRC2 activates interferon-stimulated genes indirectly by repressing miRNAs in glioblastoma
Polycomb repressive complex 2 (PRC2) is a chromatin binding complex that represses gene expression by methylating histone H3 at K27 to establish repressed chromatin domains. PRC2 can either regulate genes directly through the methyltransferase activity of its component EZH2 or indirectly by regulati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742368/ https://www.ncbi.nlm.nih.gov/pubmed/31513636 http://dx.doi.org/10.1371/journal.pone.0222435 |