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Inhibition of gap junctional intercellular communication by an anti-migraine agent, flunarizine

Gap junctions (GJs), which consist of proteins called connexins, are intercellular channels that allow the passage of ions, second messengers, and small molecules. GJs and connexins are considered as emerging therapeutic targets for various diseases. Previously, we screened numerous compounds using...

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Detalles Bibliográficos
Autores principales: Yeo, Joo Hye, Choi, Eun Ju, Lee, Jinu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742374/
https://www.ncbi.nlm.nih.gov/pubmed/31513635
http://dx.doi.org/10.1371/journal.pone.0222326