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Enhanced detection of prion infectivity from blood by preanalytical enrichment with peptoid-conjugated beads

Prions cause transmissible infectious diseases in humans and animals and have been found to be transmissible by blood transfusion even in the presymptomatic stage. However, the concentration of prions in body fluids such as blood and urine is extremely low; therefore, direct diagnostic tests on such...

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Detalles Bibliográficos
Autores principales: Hornemann, Simone, Schwarz, Petra, Rushing, Elisabeth J., Connolly, Michael D., Zuckermann, Ronald N., Yam, Alice Y., Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742390/
https://www.ncbi.nlm.nih.gov/pubmed/31513666
http://dx.doi.org/10.1371/journal.pone.0216013