GRAM: A GeneRAlized Model to predict the molecular effect of a non-coding variant in a cell-type specific manner

There has been much effort to prioritize genomic variants with respect to their impact on “function”. However, function is often not precisely defined: sometimes it is the disease association of a variant; on other occasions, it reflects a molecular effect on transcription or epigenetics. Here, we c...

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Detalles Bibliográficos
Autores principales: Lou, Shaoke, Cotter, Kellie A., Li, Tianxiao, Liang, Jin, Mohsen, Hussein, Liu, Jason, Zhang, Jing, Cohen, Sandra, Xu, Jinrui, Yu, Haiyuan, Rubin, Mark A., Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742416/
https://www.ncbi.nlm.nih.gov/pubmed/31469829
http://dx.doi.org/10.1371/journal.pgen.1007860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742416/
https://www.ncbi.nlm.nih.gov/pubmed/31469829
http://dx.doi.org/10.1371/journal.pgen.1007860

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