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Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker

Deleterious mutations in patchd1 domain containing 1 (PTCHD1) gene have been identified in patients with intellectual disability and/or autism spectrum disorder (ASD). To clarify the causal relationship between Ptchd1 deficiency and behavioral defects relevant to neurodevelopmental disorders, we gen...

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Detalles Bibliográficos
Autores principales: Murakami, Yuki, Imamura, Yukio, Saito, Kuniaki, Sakai, Daisuke, Motoyama, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742629/
https://www.ncbi.nlm.nih.gov/pubmed/31515500
http://dx.doi.org/10.1038/s41598-019-49781-y