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Activation of BNIP3-mediated mitophagy protects against renal ischemia–reperfusion injury

Acute kidney injury (AKI) is a syndrome of abrupt loss of renal functions. The underlying pathological mechanisms of AKI remain largely unknown. BCL2-interacting protein 3 (BNIP3) has dual functions of regulating cell death and mitophagy, but its pathophysiological role in AKI remains unclear. Here,...

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Detalles Bibliográficos
Autores principales: Tang, Chengyuan, Han, Hailong, Liu, Zhiwen, Liu, Yuxue, Yin, Lijun, Cai, Juan, He, Liyu, Liu, Yu, Chen, Guochun, Zhang, Zhuohua, Yin, Xiao-Ming, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742651/
https://www.ncbi.nlm.nih.gov/pubmed/31515472
http://dx.doi.org/10.1038/s41419-019-1899-0