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Activation of TFEB ameliorates dedifferentiation of arterial smooth muscle cells and neointima formation in mice with high-fat diet

Autophagy is recently implicated in regulating vascular smooth muscle cell (SMC) homeostasis and in the pathogenesis of vascular remodeling. Transcription factor EB (TFEB) is a master regulator of autophagy signaling pathways. However, the molecular mechanisms and functional roles of TFEB in SMC hom...

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Detalles Bibliográficos
Autores principales: Wang, Yun-Ting, Li, Xiang, Chen, Jiajie, McConnell, Bradley K., Chen, Li, Li, Pin-Lan, Chen, Yang, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742653/
https://www.ncbi.nlm.nih.gov/pubmed/31515484
http://dx.doi.org/10.1038/s41419-019-1931-4