Histone deacetylase 6 inhibition rescues axonal transport impairments and prevents the neurotoxicity of HIV-1 envelope protein gp120

Despite successful antiretroviral drug therapy, a subset of human immunodeficiency virus-1 (HIV)-positive individuals still display synaptodendritic simplifications and functional cognitive impairments referred to as HIV-associated neurocognitive disorders (HANDs). The neurological damage observed i...

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Detalles Bibliográficos
Autores principales: Wenzel, Erin D., Speidell, Andrew, Flowers, Sarah A., Wu, Chengbiao, Avdoshina, Valeria, Mocchetti, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742654/
https://www.ncbi.nlm.nih.gov/pubmed/31515470
http://dx.doi.org/10.1038/s41419-019-1920-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742654/
https://www.ncbi.nlm.nih.gov/pubmed/31515470
http://dx.doi.org/10.1038/s41419-019-1920-7

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