Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading

Studies of cellular mechano-signaling have often utilized static models that do not fully replicate the dynamics of living tissues. Here, we examine the time-dependent response of primary human mesenchymal stem cells (hMSCs) to cyclic tensile strain (CTS). At low-intensity strain (1 h, 4% CTS at 1 H...

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Detalles Bibliográficos
Autores principales: Gilbert, Hamish T. J., Mallikarjun, Venkatesh, Dobre, Oana, Jackson, Mark R., Pedley, Robert, Gilmore, Andrew P., Richardson, Stephen M., Swift, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742657/
https://www.ncbi.nlm.nih.gov/pubmed/31515493
http://dx.doi.org/10.1038/s41467-019-11923-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742657/
https://www.ncbi.nlm.nih.gov/pubmed/31515493
http://dx.doi.org/10.1038/s41467-019-11923-1

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