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Nuclear decoupling is part of a rapid protein-level cellular response to high-intensity mechanical loading
Studies of cellular mechano-signaling have often utilized static models that do not fully replicate the dynamics of living tissues. Here, we examine the time-dependent response of primary human mesenchymal stem cells (hMSCs) to cyclic tensile strain (CTS). At low-intensity strain (1 h, 4% CTS at 1 H...
Autores principales: | Gilbert, Hamish T. J., Mallikarjun, Venkatesh, Dobre, Oana, Jackson, Mark R., Pedley, Robert, Gilmore, Andrew P., Richardson, Stephen M., Swift, Joe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742657/ https://www.ncbi.nlm.nih.gov/pubmed/31515493 http://dx.doi.org/10.1038/s41467-019-11923-1 |
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