A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome

To better understand the impact of chromatin structure on regulation of the prostate cancer transcriptome, we develop high-resolution chromatin interaction maps in normal and prostate cancer cells using in situ Hi-C. By combining the in situ Hi-C data with active and repressive histone marks, CTCF b...

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Detalles Bibliográficos
Autores principales: Rhie, Suhn Kyong, Perez, Andrew A., Lay, Fides D., Schreiner, Shannon, Shi, Jiani, Polin, Jenevieve, Farnham, Peggy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742760/
https://www.ncbi.nlm.nih.gov/pubmed/31515496
http://dx.doi.org/10.1038/s41467-019-12079-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742760/
https://www.ncbi.nlm.nih.gov/pubmed/31515496
http://dx.doi.org/10.1038/s41467-019-12079-8

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