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A high-resolution 3D epigenomic map reveals insights into the creation of the prostate cancer transcriptome
To better understand the impact of chromatin structure on regulation of the prostate cancer transcriptome, we develop high-resolution chromatin interaction maps in normal and prostate cancer cells using in situ Hi-C. By combining the in situ Hi-C data with active and repressive histone marks, CTCF b...
Autores principales: | Rhie, Suhn Kyong, Perez, Andrew A., Lay, Fides D., Schreiner, Shannon, Shi, Jiani, Polin, Jenevieve, Farnham, Peggy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742760/ https://www.ncbi.nlm.nih.gov/pubmed/31515496 http://dx.doi.org/10.1038/s41467-019-12079-8 |
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