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Cancer Cells Sense Fibers by Coiling on them in a Curvature-Dependent Manner

Metastatic cancer cells sense the complex and heterogeneous fibrous extracellular matrix (ECM) by formation of protrusions, and our knowledge of how cells physically recognize these fibers remains in its infancy. Here, using suspended ECM-mimicking isodiameter fibers ranging from 135 to 1,000 nm, we...

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Detalles Bibliográficos
Autores principales: Mukherjee, Apratim, Behkam, Bahareh, Nain, Amrinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742781/
https://www.ncbi.nlm.nih.gov/pubmed/31513975
http://dx.doi.org/10.1016/j.isci.2019.08.023