Cargando…
Cancer Cells Sense Fibers by Coiling on them in a Curvature-Dependent Manner
Metastatic cancer cells sense the complex and heterogeneous fibrous extracellular matrix (ECM) by formation of protrusions, and our knowledge of how cells physically recognize these fibers remains in its infancy. Here, using suspended ECM-mimicking isodiameter fibers ranging from 135 to 1,000 nm, we...
Autores principales: | Mukherjee, Apratim, Behkam, Bahareh, Nain, Amrinder S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742781/ https://www.ncbi.nlm.nih.gov/pubmed/31513975 http://dx.doi.org/10.1016/j.isci.2019.08.023 |
Ejemplares similares
-
Actin Filaments Couple the Protrusive Tips to the Nucleus through the I‐BAR Domain Protein IRSp53 during the Migration of Cells on 1D Fibers
por: Mukherjee, Apratim, et al.
Publicado: (2023) -
Experimental and theoretical model for the origin of coiling of cellular protrusions around fibers
por: Sadhu, Raj Kumar, et al.
Publicado: (2023) -
Aligned fibers direct collective cell migration to engineer closing and nonclosing wound gaps
por: Sharma, Puja, et al.
Publicado: (2017) -
Quantitative biophysical metrics for rapid evaluation of ovarian cancer metastatic potential
por: Mukherjee, Apratim, et al.
Publicado: (2022) -
Capturing relevant extracellular matrices for investigating cell migration
por: Keely, Patricia, et al.
Publicado: (2015)