Cargando…

Anticancer activity of a Gold(I) phosphine thioredoxin reductase inhibitor in multiple myeloma

Multiple myeloma (MM), the second most common haematological malignancy, is a clonal plasma B-cell neoplasm that forms within the bone marrow. Despite recent advancements in treatment, MM remains an incurable disease. Auranofin, a linear gold(I) phosphine compound, has previously been shown to exert...

Descripción completa

Detalles Bibliográficos
Autores principales: Sze, Jun Hui, Raninga, Prahlad V., Nakamura, Kyohei, Casey, Mika, Khanna, Kum Kum, Berners-Price, Susan J., Di Trapani, Giovanna, Tonissen, Kathryn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742860/
https://www.ncbi.nlm.nih.gov/pubmed/31514052
http://dx.doi.org/10.1016/j.redox.2019.101310