No Effect of Digoxin on Rosuvastatin Pharmacokinetics in Healthy Subjects: Utility of Oita Combination for Clinical Drug–Drug Interaction Study

This study evaluated the utility of combination of digoxin (0.25 mg) and rosuvastatin (5 mg) as a new transporter (P‐glycoprotein/breast cancer resistance protein/organic anion‐transporting polypeptide (OATP)1B1/OATP1B3) probe cocktail (Oita combination) for drug–drug interaction (DDI) studies by de...

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Detalles Bibliográficos
Autores principales: Otani, Naoyuki, Wakuda, Hirokazu, Imai, Hiromitsu, Kuranari, Masae, Ishii, Yasuyuki, Ito, Yuko, Okubo, Akihiro, Ogawa, Osamu, Takeda, Kenji, Ohyama, Tetsuji, Hasunuma, Tomoko, Uemura, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742932/
https://www.ncbi.nlm.nih.gov/pubmed/31095880
http://dx.doi.org/10.1111/cts.12646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742932/
https://www.ncbi.nlm.nih.gov/pubmed/31095880
http://dx.doi.org/10.1111/cts.12646

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