Cerebrospinal Fluid and Brain Tissue Penetration of Tenofovir, Lamivudine, and Efavirenz in Postmortem Tissues with Cryptococcal Meningitis

The central nervous system (CNS) is a known HIV reservoir, yet little is known about drug exposure in the brain. Our primary objective was to quantify exposure of three common antiretrovirals in brain tissue and compare exposures to plasma and cerebrospinal fluid (CSF). We also sought to identify po...

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Detalles Bibliográficos
Autores principales: Nicol, Melanie R., Pastick, Katelyn A., Taylor, Joneé, Namuju, Olivie C., Rhein, Joshua, Williams, Darlisha A., Meya, David B., Boulware, David R., Lukande, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742940/
https://www.ncbi.nlm.nih.gov/pubmed/31207069
http://dx.doi.org/10.1111/cts.12661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742940/
https://www.ncbi.nlm.nih.gov/pubmed/31207069
http://dx.doi.org/10.1111/cts.12661

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