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Low Avidity T Cells Do Not Hinder High Avidity T Cell Responses Against Melanoma
The efficacy of T cells depends on their functional avidity, i. e., the strength of T cell interaction with cells presenting cognate antigen. The overall T cell response is composed of multiple T cell clonotypes, involving different T cell receptors and variable levels of functional avidity. Recentl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742971/ https://www.ncbi.nlm.nih.gov/pubmed/31555299 http://dx.doi.org/10.3389/fimmu.2019.02115 |