Ligand- and Additive-Free 2-Position-Selective Trifluoromethylation of Heteroarenes Under Ambient Conditions

A highly selective copper-catalyzed trifluoromethylation of indoles is reported with the assistance of a removable directing group. This protocol provides an easy and rapid method to various 2-position-selective trifluoromethylated heteroarenes including indoles, pyrroles, benzofuran, and acetanilid...

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Detalles Bibliográficos
Autores principales: Shi, Xiaolin, Li, Xiaowei, Li, Xiangqian, Shi, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743045/
https://www.ncbi.nlm.nih.gov/pubmed/31552228
http://dx.doi.org/10.3389/fchem.2019.00613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743045/
https://www.ncbi.nlm.nih.gov/pubmed/31552228
http://dx.doi.org/10.3389/fchem.2019.00613

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