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Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initial factor that contributes to hepatic steatosis. Our previous study indicated t...

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Detalles Bibliográficos
Autores principales: Fang, Ke, Wu, Fan, Chen, Guang, Dong, Hui, Li, Jingbin, Zhao, Yan, Xu, Lijun, Zou, Xin, Lu, Fuer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743105/
https://www.ncbi.nlm.nih.gov/pubmed/31519174
http://dx.doi.org/10.1186/s12906-019-2671-9