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Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initial factor that contributes to hepatic steatosis. Our previous study indicated t...
Autores principales: | Fang, Ke, Wu, Fan, Chen, Guang, Dong, Hui, Li, Jingbin, Zhao, Yan, Xu, Lijun, Zou, Xin, Lu, Fuer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743105/ https://www.ncbi.nlm.nih.gov/pubmed/31519174 http://dx.doi.org/10.1186/s12906-019-2671-9 |
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