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TRPP2 dysfunction decreases ATP-evoked calcium, induces cell aggregation and stimulates proliferation in T lymphocytes

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is mainly characterised by the development and enlargement of renal cysts that lead to end-stage renal disease (ESRD) in adult patients. Other clinical manifestations of this pathology include hypertension, haematuria, abdominal pain,...

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Detalles Bibliográficos
Autores principales: Magistroni, Riccardo, Mangolini, Alessandra, Guzzo, Sonia, Testa, Francesca, Rapanà, Mario R., Mignani, Renzo, Russo, Giorgia, di Virgilio, Francesco, Aguiari, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743124/
https://www.ncbi.nlm.nih.gov/pubmed/31514750
http://dx.doi.org/10.1186/s12882-019-1540-6