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A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice

BACKGROUND: NY-BR-1 has been described as a breast cancer associated differentiation antigen with intrinsic immunogenicity giving rise to endogenous T and B cell responses. The current study presents the first murine tumor model allowing functional investigation of NY-BR-1-specific immune responses...

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Detalles Bibliográficos
Autores principales: Das, Krishna, Eisel, David, Vormehr, Mathias, Müller-Decker, Karin, Hommertgen, Adriane, Jäger, Dirk, Zörnig, Inka, Feuerer, Markus, Kopp-Schneider, Annette, Osen, Wolfram, Eichmüller, Stefan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743128/
https://www.ncbi.nlm.nih.gov/pubmed/31519152
http://dx.doi.org/10.1186/s12885-019-6102-6