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Long-term use of interferon-β in multiple sclerosis increases Vδ1(−)Vδ2(−)Vγ9(−) γδ T cells that are associated with a better outcome

BACKGROUND: We previously reported that Vδ2(+)Vγ9(+) γδ T cells were significantly decreased in multiple sclerosis (MS) patients without disease-modifying therapies (untreated MS) and were negatively correlated with Expanded Disability Status Scale (EDSS) scores, suggesting protective roles of Vδ2(+...

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Detalles Bibliográficos
Autores principales: Maimaitijiang, Guzailiayi, Watanabe, Mitsuru, Shinoda, Koji, Isobe, Noriko, Nakamura, Yuri, Masaki, Katsuhisa, Matsushita, Takuya, Yoshikai, Yasunobu, Kira, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743159/
https://www.ncbi.nlm.nih.gov/pubmed/31519178
http://dx.doi.org/10.1186/s12974-019-1574-5